Posterior Microphthalmos as a Genetically Heterogeneous Condition That Can Be Allelic to Nanophthalmos

Posterior microphthalmos as a genetically heterogeneous condition that can be allelic to nanophthalmos.

P osterior microphthalmos (PM) is a rare developmental defect in which affected eyes display vitreous chamber foreshortening, normal or nearly normal anterior chamber depth, and papillomacular retinal folds. While membrane-type frizzled-related protein gene (MFRP [RefSeq NM_031433]) mutations have been reported to cause severe hyperopia that resembles PM, the resulting phenotype is better chara...

“Not Everything That Is Faced Can Be Changed, but Nothing Can Be Changed Until It Is Faced”: A Response to Recent Commentaries

Fixing things that can never be broken: Soware maintenance as heterogeneous engineering

In the very last published article of his long and distinguished career, the eminent historian of computing Michael Mahoney asked a simple but profound question: “What makes the history of soŸware hard?’’ In his characteristically playful style, Mike was engaging both with an issue of central importance to historians – namely, how can we begin to come to grips with the formidable challenges of ...

Increased corneal curvature with posterior nanophthalmos.

Posterior microphthalmos is a rare condition which is characterized by the disproportionately small size of the posterior segment of the eye. The corneal diameter, central anterior chamber depth and the lens thickness are all within the normal range. We present a case of posterior microphthalmos with all normal anterior segment measurements except increased corneal curvature.

A case of acute rheumatic fever with new criteria, a disease that needs to be considered

Introduction: Acute rheumatic fever is an autoimmune disease that mainly affects the large joints. Early treatment of a throat infection following group A streptococcus prevents of acute rheumatic fever. Given the low prevalence of the disease, especially in a situation where there is excessive use of antibiotics in Iran, this study intends to report a patient with Acute rheumatic fever with mi...